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order histories, retained contact details for faster checkout, review submissions, and special promotions.
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NT5E / eNT / CD73
5'-nucleotidase, ecto (CD73)
NT5E / eNT / CD73 is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | 5'-nucleotidase, ecto (CD73) |
| Synonyms: | NT5E, 5-nucleotidase, ecto (CD73), 5'-nucleotidase, 5 nucleotidase (CD73), 5-NT, 5-nucleotidase, 5'-nucleotidase, ecto (CD73), CD73, CD73 antigen, E5NT, Ecto-5-nucleotidase, ENT, EN, NT, Purine 5-Prime-Nucleotidase, NT5, NTE |
| Target Sequences: | NM_002526 NP_002517.1 P21589 |
Publications (6)
1
Hypoxia-inducible factor-1-dependent protection from intestinal ischemia/reperfusion injury involves ecto-5'-nucleotidase (CD73) and the A2B adenosine receptor. Hart ML, Grenz A, Gorzolla IC, Schittenhelm J, Dalton JH, Eltzschig HK. Journal of immunology (Baltimore, Md. : 1950). 2011 186:4367-74.
[PubMed:21357264]
Related Antibodies: LS-B3428.
2
Simultaneous Overexpression of Functional Human HO-1, E5NT and ENTPD1 Protects Murine Fibroblasts against TNF-a-Induced Injury In Vitro. Cinti A, De Giorgi M, Chisci E, Arena C, Galimberti G, Farina L, Bugarin C, Rivolta I, Gaipa G, Smolenski RT, Cerrito MG, Lavitrano M, Giovannoni R. PloS one. 2015 10:e0141933. (WB; Human)
[Full Text Article]
[PubMed:26513260]
[PMC:PMC4626094]
3
Elevated placental adenosine signaling contributes to the pathogenesis of preeclampsia. Iriyama T, Sun K, Parchim NF, Li J, Zhao C, Song A, Hart LA, Blackwell SC, Sibai BM, Chan LN, Chan TS, Hicks MJ, Blackburn MR, Kellems RE, Xia Y. Circulation. 2015 131:730-41. (IHC; Mouse)
[Full Text Article]
[PubMed:25538227]
[PMC:PMC4751998]
Related Antibodies: LS-B2943.
☰ Filters
Products
Proteins
(25)
Type
Over-Expression Lysate
(2)
Recombinant
(23)
Target
NT5E / eNT / CD73
(25)
Application
SDS-PAGE
(1)
Publications
No
(25)
Tag
6His, C-terminus
(7)
Fc, C-terminus
(1)
GST
(1)
His
(7)
His, N-Terminal
(2)
His,C-terminus
(3)
His-T7
(1)
Myc-DDK (Flag)
(2)
Species
Bovine
(1)
Crab-eating macaque
(1)
Human
(13)
Mouse
(5)
Rat
(4)
Source
293T Cells
(1)
E. coli
(8)
HEK 293 Cells
(2)
Human
(3)
Human Cells
(4)
Mammalian Cells
(6)
Wheat Germ Extract
(1)
Purification
Purified
(8)
Low Endotoxin Level
Low endotoxin level
(15)
Biologically Active
Biologically active
(5)
E. coli
His
53.9 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
Mammalian Cells
6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
58.76 kDa
50 µg/$698; 10 µg/$356; 1 mg/$2,837; 500 µg/$1,987
HEK 293 Cells
His,C-terminus
SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The secreted recombinant human NT5E consists of 532 amino acids with the predicted molecular mass of 59.2 kDa.
50 µg/$519; 1 mg/$2,377
E. coli
His-T7
56.2 kDa
50 µg/$482; 10 µg/$287; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His, N-Terminal
57 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365; 200 µg/$484
E. coli
His, N-Terminal
53kDa
10 µg/$326; 50 µg/$722; 200 µg/$1,325; 100 µg/$1,118; 1 mg/$2,597; 500 µg/$2,094; 5 mg/$5,041; 2 mg/$2,788
Human
None
Less than 0.1 ng/mL (Less than 1 EU/µg) (determined by LAL method).
10 µg/$277; 50 µg/$395; 500 µg/$1,377; 1 mg/$1,765
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
59 kDa
10 µg/$365; 50 µg/$479
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
58.8 kDa
10 µg/$344; 50 µg/$584
HEK 293 Cells
Myc-DDK (Flag)
63.2 kDa
100 µg/$494
Human
6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
58.8 kDa
10 µg/$344; 50 µg/$657
Human
Fc, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
84.6 kDa
10 µg/$344; 50 µg/$657
Wheat Germ Extract
GST
51.81 kDa
10 µg/$479; 25 µg/$670
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
293T Cells
Myc-DDK (Flag)
63.2 kDa
20 µg/$150
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
59.4 kDa
50 µg/$997
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
59.4 kDa
50 µg/$521; 1 mg/$4,512
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
58.8kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
58.8 kDa
10 µg/$479; 50 µg/$805
E. coli
120 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
13.31 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
58.8kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
Mammalian Cells
6His, C-terminus
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
58.8 kDa
50 µg/$698; 10 µg/$356; 1 mg/$3,095; 500 µg/$1,987
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
58.8 kDa
10 µg/$344; 50 µg/$584
E. coli
His
59.5 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His
59.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
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