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NSUN4
NOP2/Sun domain family, member 4
Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.
| Gene Name: | NOP2/Sun domain family, member 4 |
| Synonyms: | NSUN4, NOL1/NOP2/Sun domain family 4, RP4-603I14.2, SHTAP |
| Target Sequences: | AK021577 BAB13847.1 Q96CB9 |
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