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NSL1
NSL1, MIS12 kinetochore complex component
NSL1 is a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X.
| Gene Name: | NSL1, MIS12 kinetochore complex component |
| Synonyms: | NSL1, C1orf48, DKFZP566O1646, DC8, MIS14 |
| Target Sequences: | NM_015471 NP_056286.3 Q96IY1 |
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