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NRXN1 / Neurexin 1

neurexin 1

Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Two neurexin genes are among the largest known in human (NRXN1 and NRXN3). By using alternate promoters, splice sites and exons, predictions of hundreds or even thousands of distinct mRNAs have been made. Most transcripts use the upstream promoter and encode alpha-neurexin isoforms; fewer transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. Alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and they interact with neurexophilins. Beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. The RefSeq Project has decided to create only a few representative transcript variants of the multitude that are possible.

Gene Name: neurexin 1
Family/Subfamily: Neurexin , Not assigned-Other
Synonyms: NRXN1, Hs.22998, KIAA0578, Neurexin I-alpha, Neurexin-1-alpha, PTHSL2, Neurexin 1, Neurexin I-beta, Neurexin I, Neurexin-1-beta, SCZD17
Target Sequences: NM_004801 NP_004792.1 Q9ULB1

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0.312 - 20 ng/ml
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).