NPRL3

nitrogen permease regulator-like 3 (S. cerevisiae)

As a component of the GATOR1 complex, inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling.

☰ Filters

Products

Proteins (6)

Antibodies (3)

Type

Over-Expression Lysate (4)

Primary (3)

Recombinant (2)

Target

NPRL3 (9)

Reactivity

Human (3)

Mouse (1)

Rat (2)

Dog (1)

Hamster (1)

Monkey (1)

Application

WB (3)

ELISA (1)

Peptide-ELISA (2)

Host

rabbit (1)

mouse (1)

goat (1)

Isotype

IgG2b,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (2)

Clone

4E6 (1)

Format

Unconjugated (3)

Epitope

aa29-42 (1)

aa86-117 (1)

Publications

No (9)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

Select

NPRL3 Antibody (aa29-42) LS-C154925

Antibody:

NPRL3 Goat anti-Mouse Polyclonal (aa29-42) Antibody

Reactivity:

Mouse, Dog, Rat, Hamster, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

NPRL3 Antibody (clone 4E6) LS-C198529

Antibody:

NPRL3 Mouse anti-Human Monoclonal (4E6) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

NPRL3 Antibody (aa86-117) LS-C393003

Antibody:

NPRL3 Rabbit anti-Human Polyclonal (aa86-117) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

Human NPRL3 Protein (Recombinant GST, N-terminus) (aa470-568) - LS-G135980

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Molecular Weight:

36.63 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human NPRL3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G73250

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.4 kDa

Price:

20 µg/$1,107

Select

Human NPRL3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G94760

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.4 kDa

Price:

20 µg/$150

Select

Human NPRL3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G94759

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63.4 kDa

Price:

20 µg/$215

Select

NPRL3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120604

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.4 kDa

Price:

100 µg/$494

Select

NPRL3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119971

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63.4 kDa

Price:

100 µg/$710

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