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NPPA / ANP
Natriuretic Peptide A
Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
| Gene Name: | Natriuretic Peptide A |
| Synonyms: | NPPA, ANF, ANP, Atriopeptin, ATFB6, Atrial natriuretic factor, CDD-ANF, Cardionatrin, Natriuretic peptides A, Prepronatriodilatin, Natriuretic peptide A, PND, Natriuretic peptide precursor A |
| Target Sequences: | NM_006172 NP_006163.1 P01160 |
Publications (3)
1
Heart Failure With Reduced Ejection Fraction Is Characterized by Systemic NEP Downregulation. Imre J Pavo, Noemi Pavo, Nina Kastner, Denise Traxler, Dominika Lukovic, Katrin Zlabinger, Andreas Spannbauer, Martin Riesenhuber, David Lorant, Philipp E Bartko, Georg Goliasch, Martin Hülsmann, Johannes Winkler, Mariann Gyöngyösi. JACC. Basic to translational science. 2020 July;5:715-726. [Full Text Article]
[PubMed:32760858]
[PMC:PMC7393434]
2
Synergy between sacubitril and valsartan leads to hemodynamic, antifibrotic, and exercise tolerance benefits in rats with preexisting heart failure. Mikhail Y Maslov, Stephan Foianini, Dita Mayer, Michael V Orlov, Mark A Lovich. American journal of physiology. Heart and circulatory physiology. 2019 Feb;316:H289-H297. [Full Text Article]
[PubMed:30461302]
3
Full Issue PDF. No authors listed. JACC. Basic to translational science. 2020 July;5:I-CX. [Full Text Article]
[PubMed:32835137]
[PMC:PMC7384789]
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Products
Proteins
(13)
Type
Over-Expression Lysate
(2)
Recombinant
(11)
Target
NPPA / ANP
(13)
Publications
No
(13)
Tag
GST
(2)
His, N-Terminal
(2)
His-GST
(3)
His-GST, N-terminus
(2)
His-S
(1)
His-S, N-terminus
(1)
Myc-DDK (Flag)
(2)
Species
Bovine
(1)
Cow
(1)
Human
(4)
Mouse
(2)
Rat
(4)
Source
293T Cells
(1)
E. coli
(10)
HEK 293 Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(2)
293T Cells
Myc-DDK (Flag)
16.71 kDa
20 µg/$150
E. coli
His-S, N-terminus
19.8kDa
10 µg/$287; 50 µg/$482; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His, N-Terminal
16.7 kDa
50 µg/$419
Wheat Germ Extract
GST
42.57 kDa
10 µg/$479; 25 µg/$670
E. coli
His-GST
43.9 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838
HEK 293 Cells
Myc-DDK (Flag)
16.71 kDa
100 µg/$494
E. coli
His, N-Terminal
13.5kDa
10 µg/$267; 50 µg/$352; 200 µg/$702; 100 µg/$562; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
E. coli
His-GST, N-terminus
43.9kDa
10 µg/$275; 50 µg/$402; 200 µg/$802; 100 µg/$642; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
E. coli
His-GST, N-terminus
46.0kDa
10 µg/$279; 50 µg/$432; 200 µg/$862; 100 µg/$690; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
E. coli
His-GST
42.5 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$3,201
E. coli
His-S
19.8 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,841
E. coli
GST
12.1 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$3,201
E. coli
His-GST
46.0 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,441
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