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NPPA / ANP

Natriuretic Peptide A

Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

Gene Name: Natriuretic Peptide A
Synonyms: NPPA, ANF, ANP, Atriopeptin, ATFB6, Atrial natriuretic factor, CDD-ANF, Cardionatrin, Natriuretic peptides A, Prepronatriodilatin, Natriuretic peptide A, PND, Natriuretic peptide precursor A
Target Sequences: NM_006172 NP_006163.1 P01160

Publications (3)

1
Heart Failure With Reduced Ejection Fraction Is Characterized by Systemic NEP Downregulation. Imre J Pavo, Noemi Pavo, Nina Kastner, Denise Traxler, Dominika Lukovic, Katrin Zlabinger, Andreas Spannbauer, Martin Riesenhuber, David Lorant, Philipp E Bartko, Georg Goliasch, Martin Hülsmann, Johannes Winkler, Mariann Gyöngyösi. JACC. Basic to translational science. 2020 July;5:715-726. [Full Text Article] [PubMed:32760858] [PMC:PMC7393434]
2
Synergy between sacubitril and valsartan leads to hemodynamic, antifibrotic, and exercise tolerance benefits in rats with preexisting heart failure. Mikhail Y Maslov, Stephan Foianini, Dita Mayer, Michael V Orlov, Mark A Lovich. American journal of physiology. Heart and circulatory physiology. 2019 Feb;316:H289-H297. [Full Text Article] [PubMed:30461302]
3
Full Issue PDF. No authors listed. JACC. Basic to translational science. 2020 July;5:I-CX. [Full Text Article] [PubMed:32835137] [PMC:PMC7384789]

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NPPA / ANP Antibody - Anti-NPPA / ANP antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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NPPA / ANP Goat anti-Human Polyclonal (aa137-150) Antibody
Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Hamster, Horse, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
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NPPA / ANP Mouse anti-Human Monoclonal (aa4-28) (23/1) Antibody
Human
IHC-P, RIA
Unconjugated
1 mg/$743
NPPA / ANP ELISA Kit
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Sandwich
96-Well Strip Plate
Pig
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
NPPA / ANP ELISA Kit
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Competitive EIA
96-Well Microplate
Mouse, Human, Rat
0.1 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$505
NPPA / ANP Antibody - Anti-NPPA / ANP antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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NPPA / ANP Rabbit anti-Human Polyclonal (aa30-56) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$525
NPPA / ANP ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, EDTA Plasma, Heparin Plasma, Serum
1 Plate/$699
NPPA / ANP ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
7.81 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$782
NPPA / ANP Antibody - Immunohistochemistry of paraffin-embedded human rectal cancer using NPPA antibodyat dilution of 1:200 (40x lens).
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NPPA / ANP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
NPPA / ANP ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
NPPA / ANP ELISA Kit
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Sandwich
96-Well Microplate
Rat
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
NPPA / ANP ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Rat
12.35 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$715
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NPPA / ANP Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IHC, RIA
FITC Conjugated
100 µl/$1,129
NPPA / ANP Antibody - Western blot of extracts of PC-3 cell lines, using NPPA antibody.
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NPPA / ANP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
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NPPA / ANP Mouse anti-Human Monoclonal (aa12-25) (A136-10-L13-10-H8) Antibody
Mouse, Rat, Hamster, Human, Monkey
ELISA
Unconjugated
10 µg/$480; 100 µg/$914
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NPPA / ANP Mouse anti-Human Monoclonal (aa40-55) (A137-M6-19-B6) Antibody
Human
ELISA
Unconjugated
10 µg/$483; 100 µg/$914
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NPPA / ANP Mouse anti-Human Monoclonal (aa1-28) Antibody
Human
ELISA
Unconjugated
10 µg/$473; 100 µg/$919
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NPPA / ANP Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA
Biotin Conjugated, Preservative Free
50 µg/$343
NPPA / ANP Antibody - 1:100 staining human uterus tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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NPPA / ANP Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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NPPA / ANP Sheep anti-Human Polyclonal (aa95-101) Antibody
Human
RIA
Unconjugated
20 µl/$498; 100 µl/$963
NPPA / ANP ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
50 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
NPPA / ANP ELISA Kit
Select
Sandwich
96-Well Strip Plate
Dog
15.63 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$748
NPPA / ANP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
16.71 kDa
20 µg/$150
NPPA / ANP Antibody - Immunohistochemical staining of paraffin-embedded Human adult heart tissue within the normal limits using anti-NPPA mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.5) at 120 oC for 3 min. (1:500)
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NPPA / ANP Mouse anti-Human Monoclonal (aa26-153) (OTI4H4) Antibody
Human
IHC, WB
Unconjugated
100 µl/$434
NPPA / ANP Antibody - IHC analysis of ANP using anti-ANP antibody. ANP was detected in paraffin-embedded section of rat cardiac muscle tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 2?g/ml rabbit anti-ANP Antibody overnight at 4?C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37?C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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NPPA / ANP Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
ELISA, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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NPPA / ANP Rabbit anti-Human Polyclonal (aa1-28) Antibody
Dog, Sheep, Pig, Human
IF, IHC, IHC-P
Unconjugated
50 µl/$572
Viewing 1-25 of 164 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).