NOT1 / CNOT1

CCR4-NOT Transcription Complex, Subunit 1

Scaffolding component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs. Involved in degradation of AU-rich element (ARE)-containing mRNAs probably via association with ZFP36. Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex via association with TNRC6A, TNRC6B or TNRC6C. Acts as a transcriptional repressor. Represses the ligand-dependent transcriptional activation by nuclear receptors. Involved in the maintenance of emryonic stem (ES) cell identity.

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Products

Antibodies (8)

Proteins (1)

Type

Primary (8)

Recombinant (1)

Target

NOT1 / CNOT1 (9)

Reactivity

Human (8)

Mouse (2)

Rat (1)

Application

IHC (4)

IHC-P (1)

WB (4)

ELISA (5)

IF (1)

IP (3)

Peptide-ELISA (1)

Host

rabbit (8)

Isotype

IgG (8)

Clonality

polyclonal pc (8)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (5)

Epitope

aa1400-1450 (1)

Publications

No (9)

Tag

GST, N-terminus (1)

Species

Human (1)

Source

Wheat Germ Extract (1)

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NOT1 / CNOT1 Antibody LS-C335614

Antibody:

NOT1 / CNOT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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NOT1 / CNOT1 Antibody LS-C808861

Antibody:

NOT1 / CNOT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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NOT1 / CNOT1 Antibody LS-C677570

Antibody:

NOT1 / CNOT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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NOT1 / CNOT1 Antibody (HRP) LS-C677571

Antibody:

NOT1 / CNOT1 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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NOT1 / CNOT1 Antibody (Biotin) LS-C677569

Antibody:

NOT1 / CNOT1 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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NOT1 / CNOT1 Antibody (FITC) LS-C677568

Antibody:

NOT1 / CNOT1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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NOT1 / CNOT1 Antibody LS-C664674

Antibody:

NOT1 / CNOT1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

NOT1 / CNOT1 Antibody (aa1400-1450) LS-C763296

Antibody:

NOT1 / CNOT1 Rabbit anti-Human Polyclonal (aa1400-1450) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295

Select

Human NOT1 / CNOT1 Protein (Recombinant GST, N-terminus) (aa2278-2375) - LS-G61902

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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