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NOD1

nucleotide-binding oligomerization domain containing 1

NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.

Gene Name: nucleotide-binding oligomerization domain containing 1
Synonyms: NOD1, CARD4, CLR7.1, NLRC1
Target Sequences: NM_006092 NP_006083.1 Q9Y239

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Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
NOD1 (6)
No (6)
GST (1)
GST, N-terminus (2)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (3)
Purified (1)
NOD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
107.5 kDa
100 µg/$494
NOD1 Protein - Recombinant Nucleotide Binding Oligomerization Domain Containing Protein 1 By SDS-PAGE
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E. coli
His-T7
28.0 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
NOD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
107.5 kDa
20 µg/$150
NOD1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NOD1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NOD1 Protein - 12.5% SDS-PAGE of human NOD1 stained with Coomassie Blue
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Wheat Germ Extract
GST
134.1 kDa
10 µg/$479; 25 µg/$670
Viewing 1-6 of 6 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).