NOD1

nucleotide-binding oligomerization domain containing 1

NOD1 is a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

NOD1 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (2)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (3)

Purification

Purified (1)

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NOD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100719

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107.5 kDa

Price:

100 µg/$494

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Human NOD1 Protein (Recombinant His-T7) (aa612-826) - LS-G16081

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.0 kDa

Price:

10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198

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Human NOD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86703

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

107.5 kDa

Price:

20 µg/$150

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Human NOD1 Protein (Recombinant GST, N-terminus) (aa91-190) - LS-G61492

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human NOD1 Protein (Recombinant GST, N-terminus) (aa1-93) - LS-G61493

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human NOD1 Protein (Recombinant GST) (Full Length) - LS-G32118

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

134.1 kDa

Price:

10 µg/$479; 25 µg/$670

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