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NOC2L

nucleolar complex associated 2 homolog (S. cerevisiae)

Acts as an inhibitor of histone acetyltransferase activity; prevents acetylation of all core histones by the EP300/p300 histone acetyltransferase at p53/TP53-regulated target promoters in a histone deacetylases (HDAC)-independent manner. Acts as a transcription corepressor of p53/TP53- and TP63-mediated transactivation of the p21/CDKN1A promoter. Involved in the regulation of p53/TP53-dependent apoptosis. Associates together with TP63 isoform TA*-gamma to the p21/CDKN1A promoter.

Gene Name: nucleolar complex associated 2 homolog (S. cerevisiae)
Synonyms: NOC2L, DKFZP564C186, NET7, NET15, NIR, NOC2-like protein, Novel INHAT repressor, Protein NOC2 homolog
Target Sequences: NM_015658 NP_056473.2 Q9Y3T9

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Proteins (3)
Over-Expression Lysate (2)
Recombinant (1)
NOC2L (3)
No (3)
GST (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
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293T Cells
Myc-DDK (Flag)
84.7 kDa
20 µg/$150
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HEK 293 Cells
Myc-DDK (Flag)
84.7 kDa
100 µg/$494
NOC2L Protein - 12.5% SDS-PAGE of human NOC2L stained with Coomassie Blue
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Wheat Germ Extract
GST
111.3 kDa
2 µg/$439
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).