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NME2

NME/NM23 nucleoside diphosphate kinase 2

Major role in the synthesis of nucleoside triphosphates other than ATP. Negatively regulates Rho activity by interacting with AKAP13/LBC. Acts as a transcriptional activator of the MYC gene; binds DNA non-specifically (PubMed:8392752). Exhibits histidine protein kinase activity.

Gene Name:	NME/NM23 nucleoside diphosphate kinase 2
Synonyms:	NME2, Histidine protein kinase NDKB, NDKB, NM23-H2, PUF, NDP kinase B, NDPK-B, C-myc transcription factor, NDK B, NDPKB, NM23, NM23B
Target Sequences:	NM_002512 NP_002503.1 P22392

Publications (1)

Full Spectrum of Postnatal Tooth Phenotypes in a Novel Irf6 Cleft Lip Model. Chu EY, Tamasas B, Fong H, Foster BL, LaCourse MR, Tran AB, Martin JF, Schutte BC, Somerman MJ, Cox TC. Journal of dental research. 2016 October;95:1265-73. (Human) [Full Text Article] [PubMed:27369589] [PMC:PMC5076757] Related Antibodies: LS-B9880.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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