NLRP2 / NALP2

NLR family, pyrin domain containing 2

Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.

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ELISA Kits (2)

Type

Custom (1)

Sandwich (1)

Target

NLRP2 / NALP2 (2)

Reactivity

Human (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (1)

Publications

No (2)

Sample Type

Plasma (1)

Serum (1)

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Human NLRP2 / NALP2 (Custom ELISA) ELISA Kit - LS-F50669

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$823

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Human NLRP2 / NALP2 (Sandwich ELISA) ELISA Kit - LS-F66848

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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