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NLN / Neurolysin is a member of the metallopeptidase M3 protein family that cleaves neurotensin at the Pro10-Tyr11 bond, leading to the formation of neurotensin(1-10) and neurotensin(11-13). The encoded protein is likely involved in the termination of the neurotensinergic signal in the central nervous system and in the gastrointestinal tract.
Gene Name: | neurolysin (metallopeptidase M3 family) |
Family/Subfamily: | Protease , Metallopeptidase M3 |
Synonyms: | NLN, AGTBP, Angiotensin binding protein, Angiotensin-binding protein, Endopeptidase 24.16, Endopeptidase 3.4.24.16, Neurolysin, Neurolysin, mitochondrial, KIAA1226, MEP, MOP, Neurotensin endopeptidase, EP24.16, Microsomal endopeptidase, Mitochondrial oligopeptidase M |
Target Sequences: | NM_020726 NP_065777.1 Q9BYT8 |
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