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NLGN4X / KIAA1260 is a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants.
Gene Name: | neuroligin 4, X-linked |
Synonyms: | NLGN4X, AUTSX2, HLNX, HNLX, KIAA1260, HNL4X, NLGN, Neuroligin 4, Neuroligin 4, X-linked, Neuroligin X, Neuroligin-4, X-linked, ASPGX2, NLGN4 |
Target Sequences: | AB033086 NP_065793.1 Q8N0W4 |
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