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NKX2-6
NK2 homeobox 6
NKX2-6 is a homeobox-containing protein that belongs to the NK-2 homeobox family. This protein is a vertebrate homolog of Drosophila homeobox-containing protein called 'tinman', which has been shown to be essential for development of the heart-like dorsal vessel. In conjunction with related gene, NKX2-5, this gene may play a role in both pharyngeal and cardiac embryonic development. Mutations in this gene are associated with persistent truncus arteriosus.
| Gene Name: | NK2 homeobox 6 |
| Synonyms: | NKX2-6, CSX2, Homeobox protein NKX2.6, Homeobox protein NK2 homolog F, Homeobox protein Nkx-2.6, NKX4-2, NKX2F, Tinman paralog, NK2 homeobox 6 |
| Target Sequences: | NM_001136271 NP_001129743.2 A6NCS4 |
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