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NIT2

nitrilase family, member 2

Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.

Gene Name:	nitrilase family, member 2
Synonyms:	NIT2, Omega-amidase NIT2, Nit protein 2, Nitrilase family, member 2, Nitrilase homolog 2
Target Sequences:	NM_020202 NP_064587.1 Q9NQR4

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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