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Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha-ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle.
Gene Name: | nitrilase family, member 2 |
Synonyms: | NIT2, Omega-amidase NIT2, Nit protein 2, Nitrilase family, member 2, Nitrilase homolog 2 |
Target Sequences: | NM_020202 NP_064587.1 Q9NQR4 |
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