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The helix-loop-helix (HLH) proteins are a family of putative transcription factors, some of which have been shown to play an important role in growth and development of a wide variety of tissues and species. Four members of this family have been clearly implicated in tumorigenesis via their involvement in chromosomal translocations in lymphoid tumors: MYC (MIM 190080), LYL1 (MIM 151440), E2A (MIM 147141), and SCL (MIM 187040).
Gene Name: | nescient helix loop helix 1 |
Synonyms: | NHLH1, BHLHa35, Helix-loop-helix protein 1, HEN-1, HEN1, NSCL, Nescient helix loop helix 1, NSCL1, NSCL-1 |
Target Sequences: | NM_005598 NP_005589.1 Q02575 |
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