NGLY1

N-glycanase 1

Specifically deglycosylates the denatured form of N-linked glycoproteins in the cytoplasm and assists their proteasome-mediated degradation. Cleaves the beta-aspartyl-glucosamine (GlcNAc) of the glycan and the amide side chain of Asn, converting Asn to Asp. Prefers proteins containing high-mannose over those bearing complex type oligosaccharides. Can recognize misfolded proteins in the endoplasmic reticulum that are exported to the cytosol to be destroyed and deglycosylate them, while it has no activity toward native proteins. Deglycosylation is a prerequisite for subsequent proteasome-mediated degradation of some, but not all, misfolded glycoproteins.

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Products

Antibodies (7)

Type

Primary (7)

Target

NGLY1 (7)

Reactivity

Human (7)

Application

IHC (1)

IHC-P (1)

WB (6)

IP (1)

Host

rabbit (7)

Isotype

IgG (2)

Clonality

polyclonal pc (7)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (4)

Epitope

Internal (4)

C-Terminus (1)

aa250-300 (1)

Publications

No (7)

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NGLY1 Antibody (Internal) LS-C345852

Antibody:

NGLY1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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NGLY1 Antibody (Internal, HRP) LS-C480959

Antibody:

NGLY1 Rabbit anti-Human Polyclonal (Internal) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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NGLY1 Antibody (Internal, Biotin) LS-C480957

Antibody:

NGLY1 Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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NGLY1 Antibody (Internal, FITC) LS-C480958

Antibody:

NGLY1 Rabbit anti-Human Polyclonal (Internal) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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NGLY1 Antibody (C-Terminus) LS-C144866

Antibody:

NGLY1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

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NGLY1 Antibody (aa250-300) LS-C763060

Antibody:

NGLY1 Rabbit anti-Human Polyclonal (aa250-300) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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NGLY1 Antibody LS-C816814

Antibody:

NGLY1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$412

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