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NFYB
nuclear transcription factor Y, beta
NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.
| Gene Name: | nuclear transcription factor Y, beta |
| Synonyms: | NFYB, CBF-A, CBF-B, HAP3, NF-YB |
| Target Sequences: | NM_006166 NP_006157.1 P25208 |
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