NFKBIZ / IKBZ

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. May promote apoptosis.

☰ Filters

Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

NFKBIZ / IKBZ (7)

Publications

No (7)

Tag

GST (1)

His-T7 (2)

Myc-DDK (Flag) (4)

Species

Human (4)

Mouse (1)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

NFKBIZ / IKBZ Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122088

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.2 kDa

Price:

100 µg/$494

Select

Human NFKBIZ / IKBZ Protein (Recombinant GST) (Full Length) - LS-G34974

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

104.5 kDa

Price:

10 µg/$479; 25 µg/$670

Select

Human NFKBIZ / IKBZ Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86495

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

68.2 kDa

Price:

20 µg/$150

Select

Human NFKBIZ / IKBZ Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G86496

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.5 kDa

Price:

20 µg/$215

Select

NFKBIZ / IKBZ Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109224

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.5 kDa

Price:

100 µg/$710

Select

Human NFKBIZ / IKBZ Protein (Recombinant His-T7) (aa422-651) - LS-G14848

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

Select

Mouse NFKBIZ / IKBZ Protein (Recombinant His-T7) (aa414-654) - LS-G14849

Source:

E. coli

Tag:

His-T7

Molecular Weight:

30.4 kDa

Price:

10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

Viewing 1-7 of 7 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.