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Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon-regulatory factor (IRF) signaling pathways. Contributes to the negative regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli.
Gene Name: | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
Synonyms: | NFKBIL1, I-kappa-B-like protein, NFKBIL, IkappaBL, IKBL |
Target Sequences: | NM_005007 NP_004998.3 Q9UBC1 |
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