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NFE2L3

nuclear factor, erythroid 2-like 3

NFE2L3 is a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.

Gene Name: nuclear factor, erythroid 2-like 3
Synonyms: NFE2L3, NFE2-related factor 3, NF-E2-related factor 3, NRF3
Target Sequences: NM_004289 NP_004280.5 Q9Y4A8

Publications (2)

1
NFE2L3 promotes malignant behavior and EMT of human hepatocellular carcinoma (HepG2) cells via Wnt/ß-catenin pathway. Yonggang Ren, Yujiao Wang, Shuai Hao, Yuhan Yang, Wendong Xiong, Lu Qiu, Jia Tao, Aifa Tang. Journal of Cancer. 2020 October;11:6939-6949. [Full Text Article] [PubMed:33123284] [PMC:PMC7591994] Related Antibodies: LS-C430024.
2
Microarray analysis of primary epithelial and fibroblast cells in chronic rhinosinusitis without nasal polyps. S L Ball, S J Cockell, J A Wilson, D A Mann, A J Fisher. Rhinology. 2020 December;58:581-587. [Full Text Article] [PubMed:32812016] Related Antibodies: LS-B8066.

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Proteins (2)
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NFE2L3 (2)
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NFE2L3 Protein - 12.5% SDS-PAGE of human NFE2L3 stained with Coomassie Blue
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Wheat Germ Extract
GST
102.6 kDa
10 µg/$479; 25 µg/$670
NFE2L3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).