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Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
|Gene Name:||nuclear factor, erythroid 2-like 2|
|Synonyms:||NFE2L2, NF-E2-related factor 2, NFE2-related factor 2, NRF2|
|Target Sequences:||NM_006164 NP_006155.2 Q16236|
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