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NFE2L2 / NRF2
nuclear factor, erythroid 2-like 2
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
| Gene Name: | nuclear factor, erythroid 2-like 2 |
| Synonyms: | NFE2L2, NF-E2-related factor 2, NFE2-related factor 2, NRF2 |
| Target Sequences: | NM_006164 NP_006155.2 Q16236 |
Publications (6)
1
Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription. Yang L, Calingasan NY, Thomas B, Chaturvedi RK, Kiaei M, Wille EJ, Liby KT, Williams C, Royce D, Risingsong R, Musiek ES, Morrow JD, Sporn M, Beal MF. PloS one. 2009 4:e5757. (WB)
[PubMed:19484125]
[PMC:PMC2684590]
2
Up-regulation of human CYP2J2 in HepG2 cells by butylated hydroxyanisole is mediated by c-Jun and Nrf2. Lee AC, Murray M. Molecular pharmacology. 2010 77:987-94. (WB)
[PubMed:20194533]
3
Adrenergic regulation during acute hepatic infection with Entamoeba histolytica in the hamster: involvement of oxidative stress, Nrf2 and NF-KappaB. Aldaba-Muruato LR, Muñoz-Ortega MH, Macías-Pérez JR, Pulido-Ortega J, Martínez-Hernández SL, Ventura-Juárez J. Parasite (Paris, France). 2017 24:46. (Human)
[Full Text Article]
[PubMed:29185982]
[PMC:PMC5706999]
Related Antibodies: LS-C154863.
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NFE2L2 / NRF2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal (Ser40) Antibody
Mouse, Rat, Human
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µl/$391
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Mouse, Dog, Guinea pig, Rat, Pig, Bat, Orangutan, Chimpanzee, Human, Monkey
Compet, ELISA, ICC, IHC, IP, WB
Biotin Conjugated
100 µl/$442
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal (aa30-59) Antibody
Human
WB
Unconjugated
400 µl/$393
NFE2L2 / NRF2 Goat anti-Human Polyclonal (aa445-458) Antibody
Mouse, Dog, Bovine, Rat, Hamster, Bat, Human
Peptide-ELISA, WB
Unconjugated
100 µg/$493
NFE2L2 / NRF2 Mouse anti-Human Monoclonal (aa356-589) (1A6G6) Antibody
Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$447
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal (Leu593) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
NFE2L2 / NRF2 Mouse anti-Human Monoclonal (437C2a) Antibody
Human
DB, WB
Unconjugated
100 µg/$486
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal (Ser40) Antibody
Human
WB
Unconjugated
400 µl/$393
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Sandwich
96-Well Strip Plate
Mouse
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
NFE2L2 / NRF2 Mouse anti-Human Monoclonal (aa330-605) (OTI8A10) Antibody
Human
WB
Unconjugated
100 µl/$434
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC, WB
Unconjugated
100 µg/$442
NFE2L2 / NRF2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$547
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal (C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal (aa30-59) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$1,002
NFE2L2 / NRF2 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
50 µg/$527
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NFE2L2 / NRF2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
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