NF45 / ILF2

interleukin enhancer binding factor 2

NF45 / ILF2 is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14.

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Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

NF45 / ILF2 (7)

Publications

No (7)

Tag

GST (2)

GST, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (6)

Source

293T Cells (1)

Bacteria (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human NF45 / ILF2 Protein (Recombinant GST, N-terminus) - LS-G43346

Source:

Bacteria

Tag:

GST, N-terminus

Molecular Weight:

60 kDa

Price:

100 µg/$350

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Human NF45 / ILF2 Protein (Recombinant GST) (Full Length) - LS-G29053

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

69.5 kDa

Price:

10 µg/$479; 25 µg/$670

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Human NF45 / ILF2 Protein (Recombinant GST) (Full Length) - LS-G22044

Source:

E. coli

Tag:

GST

Molecular Weight:

70.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human NF45 / ILF2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66434

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.9 kDa

Price:

20 µg/$1,107

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Human NF45 / ILF2 Protein (Recombinant GST, N-terminus) (aa151-250) - LS-G58994

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human NF45 / ILF2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77702

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.9 kDa

Price:

20 µg/$150

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NF45 / ILF2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100321

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.9 kDa

Price:

100 µg/$494

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