NEUROD2

neuronal differentiation 2

Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter. Critical factor essential for the repression of the genetic program for neuronal differentiation; prevents the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. Induces transcription of ZEB1, which in turn represses neuronal differentiation by down-regulating REST expression. Plays a role in the establishment and maturation of thalamocortical connections; involved in the segregation of thalamic afferents into distinct barrel domains within layer VI of the somatosensory cortex. Involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Associates with chromatin to the DPYSL3 E box-containing promoter.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

NEUROD2 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human NEUROD2 Protein (Recombinant GST, N-terminus) (aa266-375) - LS-G59385

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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NEUROD2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115494

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.2 kDa

Price:

100 µg/$494

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Human NEUROD2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77648

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.2 kDa

Price:

20 µg/$150

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Human NEUROD2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66418

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

41.2 kDa

Price:

20 µg/$1,107

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Human NEUROD2 Protein (Recombinant His, N-Terminal) - LS-G145160

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

41.2 kDa

Price:

50 µg/$419

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Human NEUROD2 Protein (Recombinant GST) (Full Length) - LS-G29497

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

67.7 kDa

Price:

2 µg/$439

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