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The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis.
Gene Name: | NEL-like 2 (chicken) |
Synonyms: | NELL2, NEL-like 2 (chicken), NEL-like protein 2, Nel (chicken)-like 2, Nel-related protein 2 |
Target Sequences: | NM_006159 NP_006150.1 Q99435 |
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