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NELFB / COBRA1

negative elongation factor complex member B

Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. May be able to induce chromatin unfolding.

Gene Name: negative elongation factor complex member B
Synonyms: NELFB, Cofactor of BRCA1, COBRA1, RP13-122B23.3, KIAA1182, Negative elongation factor B, NELF-B
Target Sequences: NM_015456 NP_056271.2 Q8WX92

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
NELFB / COBRA1 (5)
No (5)
GST (2)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
NELFB / COBRA1 Protein - 12.5% SDS-PAGE of human COBRA1 stained with Coomassie Blue
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Wheat Germ Extract
GST
77.99 kDa
10 µg/$479; 25 µg/$670
NELFB / COBRA1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
65.5 kDa
100 µg/$710
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E. coli
GST
49.2 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
NELFB / COBRA1 Protein - Purified recombinant protein NELFB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
65.5 kDa
20 µg/$1,107
NELFB / COBRA1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
65.5 kDa
20 µg/$215
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).