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Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation.
Gene Name: | NIMA-related kinase 11 |
Family/Subfamily: | Protein Kinase , NEK |
Synonyms: | NEK11, NimA-related protein kinase 11, NIMA-related kinase 11 |
Target Sequences: | NM_024800 NP_079076.3 Q8NG66 |
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