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NDRG1

N-myc downstream regulated 1

Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking, notably of the Schwann cell, and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy.

Gene Name: N-myc downstream regulated 1
Synonyms: NDRG1, CMT4D, DRG-1, GC4, HMSNL, Protein regulated by oxygen-1, PROXY1, Protein NDRG1, TARG1, TDD5, NDR1, RTP, CAP43, N-myc downstream regulated 1, NMSL, RIT42
Target Sequences: NM_006096 NP_006087.2 Q92597

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Products
Proteins (10)
Over-Expression Lysate (4)
Recombinant (6)
NDRG1 (10)
No (10)
6His, N-terminus (2)
GST (1)
His (1)
Myc-DDK (Flag) (6)
Human (8)
293T Cells (2)
E. coli (3)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (2)
Low endotoxin level (2)
Biologically active (1)
NDRG1 Protein - Purified recombinant protein NDRG1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42.7 kDa
20 µg/$1,107
NDRG1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.7 kDa
100 µg/$494
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
45.0 kDa
10 µg/$317; 50 µg/$524
NDRG1 Protein - 12.5% SDS-PAGE of human NDRG1 stained with Coomassie Blue
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Wheat Germ Extract
GST
69.08 kDa
10 µg/$479; 25 µg/$670
NDRG1 Protein - Purified recombinant protein NDRG1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42.7 kDa
20 µg/$1,107
Select
293T Cells
Myc-DDK (Flag)
42.7 kDa
20 µg/$150
NDRG1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
42.7 kDa
20 µg/$150
NDRG1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
42.7 kDa
100 µg/$494
NDRG1 Protein
Select
E. coli
His
Biologically active
100 µg/$317; 500 µg/$526; 20 µg/$245
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
45kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
Viewing 1-10 of 10 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).