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NDE1

nudE neurodevelopment protein 1

Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex.

Gene Name: nudE neurodevelopment protein 1
Synonyms: NDE1, HOM-TES-87, LIS4, NUDE, NUDE1
Target Sequences: NM_001143979 NP_001137451.1 Q9NXR1

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Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
NDE1 (8)
No (8)
GST (1)
His (1)
Myc-DDK (Flag) (6)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (1)
Purified (2)
NDE1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
37.5 kDa
100 µg/$494
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293T Cells
Myc-DDK (Flag)
37.5 kDa
20 µg/$150
NDE1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
37.5 kDa
20 µg/$150
NDE1 Protein - 12.5% SDS-PAGE of human NDE1 stained with Coomassie Blue
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Wheat Germ Extract
GST
62.59 kDa
10 µg/$479; 25 µg/$670
NDE1 Protein - Purified recombinant protein NDE1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
37.5 kDa
20 µg/$1,107
NDE1 Protein - Purified recombinant protein NDE1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
37.5 kDa
20 µg/$1,107
NDE1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
37.5 kDa
100 µg/$494
NDE1 Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).