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NCS1 / Neuronal Calcium Sensor
neuronal calcium sensor 1
Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel.
| Gene Name: | neuronal calcium sensor 1 |
| Synonyms: | NCS1, Frequenin (Drosophila) homolog, FREQ, FLUP, Frequenin homolog, Neuronal calcium sensor 1, Frequenin homolog (Drosophila), Frequenin-like protein, NCS-1 |
| Target Sequences: | NM_014286 NP_055101.2 P62166 |
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