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NCKIPSD / AF3P21
NCK interacting protein with SH3 domain
Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.
| Gene Name: | NCK interacting protein with SH3 domain |
| Synonyms: | NCKIPSD, AF3P21, Dia-interacting protein 1, DIP-1, DIP1, Dia interacting protein, DIP, ORF1, SH3 adapter protein SPIN90, SPIN90, WISH, WASLBP, VIP54 |
| Target Sequences: | NM_016453 NP_057537.1 Q9NZQ3 |
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