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NBR1

neighbor of BRCA1 gene 1

NBR1 was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: neighbor of BRCA1 gene 1
Synonyms: NBR1, 1A1-3B, 1A13B, CA125, M17S2, MIG19, Migration-inducing protein 19, Neighbor of BRCA1 gene 1, KIAA0049, Next to BRCA1 gene 1 protein, Protein 1A1-3B
Target Sequences: NM_005899 NP_005890.2 Q14596

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Products
Proteins (8)
Over-Expression Lysate (6)
Recombinant (2)
NBR1 (8)
No (8)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (6)
Human (5)
293T Cells (3)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
NBR1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NBR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
107.2 kDa
100 µg/$710
NBR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
107.2 kDa
100 µg/$710
NBR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
107.2 kDa
100 µg/$710
NBR1 Protein - 12.5% SDS-PAGE of human NBR1 stained with Coomassie Blue
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Wheat Germ Extract
GST
133.8 kDa
2 µg/$439
NBR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
107.2 kDa
20 µg/$215
NBR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
107.2 kDa
20 µg/$215
NBR1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
107.2 kDa
20 µg/$215
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).