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NANS

N-acetylneuraminic acid synthase

NANS is an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

Gene Name: N-acetylneuraminic acid synthase
Synonyms: NANS, SAS, Sialic acid phosphate synthase, Sialic acid synthase, N-acetylneuraminate synthase
Target Sequences: NM_018946 NP_061819.2 Q9NR45

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Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
NANS (8)
No (8)
6His, N-terminus (2)
GST (1)
GST, N-terminus (1)
His (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (2)
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293T Cells
Myc-DDK (Flag)
40.1 kDa
20 µg/$150
NANS Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
40.1 kDa
100 µg/$494
NANS Protein - 12.5% SDS-PAGE of human NANS stained with Coomassie Blue
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Wheat Germ Extract
GST
66.7 kDa
10 µg/$479; 25 µg/$670
NANS Protein - Purified recombinant protein NANS was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
40.1 kDa
20 µg/$1,107
NANS Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
NANS Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
42.4 kDa
10 µg/$368; 50 µg/$504
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
42.4kD
10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).