Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. In the SOSS complex, acts as a sensor of single-stranded DNA that binds to single-stranded DNA, in particular to polypyrimidines. The SOSS complex associates with DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. Required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways.
|Gene Name:||nucleic acid binding protein 2|
|Synonyms:||NABP2, LP3587, HSSB1, OBFC2B, Sensor of ssDNA subunit B1, SSB1, SOSS-B1, Nucleic acid binding protein 2, Nucleic acid-binding protein 2, SOSS complex subunit B1|
|Target Sequences:||NM_024068 NP_076973.1 Q9BQ15|
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.