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This gene encodes a protein that is abundantly expressed in cardiac tissue. The encoded protein localizes to intercalated discs in cardiomyocytes and functions as an activator of Rho-dependent serum-response factor signaling. Alternative splicing results in multiple transcript variants. Readthrough transcription also exists between this gene and the neighboring downstream gene POLR2M (polymerase (RNA) II (DNA directed) polypeptide M) and is represented with GeneID: 145781.
Gene Name: | myocardial zonula adherens protein |
Synonyms: | MYZAP, GCOM1, Gup, MYOZAP |
Target Sequences: | NM_001018100 NP_001018110.1 |
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