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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Myosin VI / MYO6

Myosin VI

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding. Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration. Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. Appears to be involved in a very early step of clathrin-mediated endocytosis in polarized epithelial cells. May act as a regulator of F-actin dynamics. May play a role in transporting DAB2 from the plasma membrane to specific cellular targets. Required for structural integrity of inner ear hair cells.

Gene Name: Myosin VI
Synonyms: MYO6, DFNB37, DFNA22, Myosin VI, Myosin-VI, Unconventional myosin-VI, Unconventional myosin-6, KIAA0389
Target Sequences: AL136093 CAI42823.1 Q9UM54

Filtered by: None
Target
Myosin VI / MYO6 (16)
Reactivity
Human (16)
Mouse (4)
Rat (3)
Chicken (1)
Pig (2)
Swine (1)
Application
IHC (11)
IHC-P (2)
WB (16)
ELISA (12)
ICC (6)
IF (8)
IP (1)
Host
rabbit (15)
mouse (1)
Isotype
IgG (10)
IgG2a,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (15)
Clone
2E12 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (10)
Epitope
aa1166-1195 (8)
40-120 aa, N-terminal (1)
N-Terminus (1)
Publications
No (16)
Showing 1-16 of 16 results

IHC-plus™ Myosin VI / MYO6 Antibody (N-Terminus) LS-B13579
Rabbit Polyclonal to Human Myosin VI / MYO6
Chicken, Rat, Pig, Mouse, Human
IHC, IHC-P, WB
Unconjugated
50µl 1mg/ml  $425.00
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE)

Myosin VI / MYO6 Antibody (aa1166-1195) LS-C164716
Rabbit Polyclonal to Human Myosin VI / MYO6
Human
IF, IHC, IHC-P, WB
Unconjugated
400µl  $325.00
MYO6 Antibody (C-term R1181) immunohistochemistry of formalin-fixed and paraffin-embedded human brain tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Confocal immunofluorescence of MYO6 Antibody (C-term R1181)with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

Myosin VI / MYO6 Antibody LS-C144660
Rabbit Polyclonal to Human Myosin VI / MYO6
Human
IHC, IP, WB
Unconjugated
100µl  $365.00

Myosin VI / MYO6 Antibody (aa1166-1195) LS-C323205
Rabbit Polyclonal (IgG) to Human Myosin VI / MYO6
Human
ELISA, IF, IHC, WB
Unconjugated
200µl  $590.00

Myosin VI / MYO6 Antibody (aa1166-1195, Biotin) LS-C263882
Rabbit Polyclonal (IgG) to Human Myosin VI / MYO6
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200µl  $740.00

Myosin VI / MYO6 Antibody (aa1166-1195, FITC) LS-C263883
Rabbit Polyclonal (IgG) to Human Myosin VI / MYO6
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200µl  $740.00

Myosin VI / MYO6 Antibody (aa1166-1195, AP) LS-C263880
Rabbit Polyclonal (IgG) to Human Myosin VI / MYO6
Human
ELISA, ICC, IF, IHC, WB
AP Conjugated
200µl  $740.00

Myosin VI / MYO6 Antibody (aa1166-1195, APC) LS-C263881
Rabbit Polyclonal (IgG) to Human Myosin VI / MYO6
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200µl  $740.00

Myosin VI / MYO6 Antibody (aa1166-1195, Azide-free, HRP) LS-C263884
Rabbit Polyclonal (IgG) to Human Myosin VI / MYO6
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

Myosin VI / MYO6 Antibody (aa1166-1195, PE) LS-C263885
Rabbit Polyclonal (IgG) to Human Myosin VI / MYO6
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200µl  $740.00

Myosin VI / MYO6 Antibody LS-C808091
Rabbit Polyclonal (IgG) to Human Myosin VI / MYO6
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Western blot Image

Myosin VI / MYO6 Antibody (clone 2E12) LS-C197736
Mouse Monoclonal [clone 2E12] (IgG2a,k) to Human Myosin VI / MYO6
Human
ELISA, WB
Unconjugated
100µg  $365.00
MYO6 monoclonal antibody (M02), clone 2E12. Western Blot analysis of MYO6 expression in MCF-7.
Detection limit for recombinant GST tagged MYO6 is 0.3 ng/ml as a capture antibody.

Myosin VI / MYO6 Antibody LS-C209179
Rabbit Polyclonal to Human Myosin VI / MYO6
Human
ELISA, WB
Unconjugated
100µl 25mg/ml  $425.00
Western Blot of Rabbit anti-Myosin-6 antibody. Lane 1: SF9 cell lysate of truncated smooth myosin. Lane 2: Jurkat lysate. Lane 3: LnCap lysate. Lane 4: Recombinant myosin VI Load: 35 ug per lane for cell lysate. 50 ng of recombinant protein. Primary antibody: Myosin 6 antibody at 1:1000 for overnight at 4 degrees C. Secondary antibody: HRP rabbit secondary antibody at 1:40,000 for 60 min at RT. Block: 5% BLOTTO overnight at 4 degrees C. Predicted/Observed size: 150 kDa for Myo6.

Myosin VI / MYO6 Antibody (40-120 aa, N-terminal) LS-C386830
Rabbit Polyclonal (IgG) to Human Myosin VI / MYO6
Mouse, Rat, Human
ELISA, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00
Western blot of Myosin VI antibody

Myosin VI / MYO6 Antibody LS-C744613
Rabbit Polyclonal to Swine Myosin VI / MYO6
Pig, Swine, Human
ELISA, WB
Unconjugated
25µl 25mg/ml  $235.00
Western Blot of rabbit anti-Myosin-6 antibody. Lane 1: SF9 cell lysate of truncated smooth myosin. Lane 2: Jurkat lysate. Lane 3: LnCap lysate. Lane 4: Recombinant myosin VI Load: 20µg per lane for cell lysate. 50ng of recombinant protein. Primary antibody: Myosin 6 antibody at 1:1000 for overnight at 4°C. Secondary antibody: HRP rabbit secondary antibody at 1:40,000 for 60 min at RT. Block: 5% BLOTTO overnight at 4°C. Predicted/Observed size: 150 kDa for Myo6.

Myosin VI / MYO6 Antibody LS-C748097
Rabbit Polyclonal (IgG) to Human Myosin VI / MYO6
Mouse, Human
WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of various cell lines, using MYO6 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Showing 1-16 of 16 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).