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MYO15A

Myosin XVA

MYO15A is an unconventional myosin. This protein differs from other myosins in that it has a long N-terminal extension preceding the conserved motor domain. Studies in mice suggest that this protein is necessary for actin organization in the hair cells of the cochlea. Mutations in this gene have been associated with profound, congenital, neurosensory, nonsyndromal deafness. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Read-through transcripts containing an upstream gene and this gene have been identified, but they are not thought to encode a fusion protein. Several alternatively spliced transcript variants have been described, but their full length sequences have not been determined.

Gene Name: Myosin XVA
Synonyms: MYO15A, Myosin XVA, MYO15, Unconventional myosin-XV, DFNB3, Myosin-XV, Unconventional myosin-15
Target Sequences: NM_016239 NP_057323.3 Q9UKN7

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Proteins (1)
Recombinant (1)
MYO15A (1)
No (1)
GST, N-terminus (1)
Human (1)
Wheat Germ Extract (1)
MYO15A Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).