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Myosins are actin-based motor proteins that function in the generation of mechanical force in eukaryotic cells. Muscle myosins are heterohexamers composed of 2 myosin heavy chains and 2 pairs of nonidentical myosin light chains. This gene encodes a member of the class II or conventional myosin heavy chains, and functions in skeletal muscle contraction. This gene is predominantly expressed in fetal skeletal muscle. This gene is found in a cluster of myosin heavy chain genes on chromosome 17. A mutation in this gene results in trismus-pseudocamptodactyly syndrome.
|Gene Name:||Myosin, heavy polypeptide 8, skeletal muscle, perinatal (MYH8)|
|Synonyms:||MYH8, MyHC-pn, gtMHC-F, MyHC-peri, myosin heavy chain 8, myosin-8|
|Target Sequences:||NM_002472 NP_002463.2 P13535|
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