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The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined.
Gene Name: | Myosin, Heavy Chain 7B, Cardiac Muscle, Beta |
Synonyms: | MYH7B, Antigen MLAA-21, DJ756N5.1, Slow A MYH14, MHC14, Myosin-7B, KIAA1512, U937-associated antigen |
Target Sequences: | AB040945 BAA96036.2 A7E2Y1 |
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