MYD88

myeloid differentiation primary response 88

The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP. Recently, MyD88 was identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and dominant negative form of MyD88 attenuates IL-1R-mediated NF-kB activation. MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor, which are members in the Toll/IL-1R family of receptors. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL-1 and IL-18, and MyD88-deficient mice lack responses to bacterial product LPS that employs Toll-like receptors 2 and 4 (TLR2 and TLR4) as the signaling receptors. MyD88 is a general adapter protein for the Toll/IL-1R family of receptors and plays an important role in the inflammatory response induced by cytokines IL-1 and IL-18 and endotoxin. MyD88 gene is expressed in many tissues.

☰ Filters

Products

Proteins (13)

Type

Over-Expression Lysate (6)

Recombinant (7)

Target

MYD88 (13)

Publications

No (13)

Tag

GST (1)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

His-GST (1)

Myc-DDK (Flag) (7)

Species

Human (8)

Mouse (1)

Rat (1)

Source

293T Cells (3)

E. coli (4)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (3)

Select

Human MYD88 Protein (Recombinant His, N-Terminal) (Ala2-Pro296) - LS-G96874

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

36 kDa

Price:

10 µg/$265; 100 µg/$365; 50 µg/$315

Select

Human MYD88 Protein (Recombinant His) - LS-G2111

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

Select

Mouse MYD88 Protein (Recombinant His) (aa32-265) - LS-G14202

Source:

E. coli

Tag:

His

Molecular Weight:

28.4 kDa

Price:

10 µg/$288; 50 µg/$482; 100 µg/$772; 200 µg/$965; 1 mg/$2,098; 500 µg/$1,627; 5 mg/$3,375; 2 mg/$2,288

Select

Human MYD88 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77491

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.1 kDa

Price:

20 µg/$150

Select

MYD88 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99760

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.1 kDa

Price:

100 µg/$494

Select

MYD88 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G128915

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.4 kDa

Price:

100 µg/$494

Select

MYD88 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129610

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.9 kDa

Price:

100 µg/$494

Select

Rat MYD88 Protein (Recombinant His-GST) (aa1-296) - LS-G24431

Source:

E. coli

Tag:

His-GST

Molecular Weight:

63.9 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

Select

Human MYD88 Protein (Recombinant GST, N-terminus) (aa31-130) - LS-G59312

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Select

Human MYD88 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77492

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.9 kDa

Price:

20 µg/$150

Select

Human MYD88 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77493

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

34.4 kDa

Price:

20 µg/$150

Select

Human MYD88 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66330

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

33.1 kDa

Price:

20 µg/$1,107

Select

Human MYD88 Protein (Recombinant GST) (Full Length) - LS-G29413

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

58.3 kDa

Price:

2 µg/$439

Viewing 1-13 of 13 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.