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B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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MYCN / N-myc
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYCN / N-myc is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog |
| Synonyms: | MYCN, BHLHe37, Neuroblastoma MYC oncogene, NMYC, ODED, Pp65/67, MODED, N-myc, N-myc proto-oncogene protein, Oncogene NMYC |
| Target Sequences: | NM_005378 NP_005369.2 P04198 |
Publications (1)
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