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MYBPC1

myosin binding protein C, slow type

MYBPC1 is a member of the myosin-binding protein C family. Myosin-binding protein C family members are myosin-associated proteins found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The encoded protein is the slow skeletal muscle isoform of myosin-binding protein C and plays an important role in muscle contraction by recruiting muscle-type creatine kinase to myosin filaments. Mutations in this gene are associated with distal arthrogryposis type I. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Name: myosin binding protein C, slow type
Synonyms: MYBPC1, MYBPCS, MYBPCC, LCCS4, Slow MyBP-C, Slow-type, Skeletal muscle C-protein
Target Sequences: NM_002465 NP_002456.2 Q00872

Publications (1)

1
Low-Intensity Training and the C5a Complement Antagonist NOX-D21 Rescue the mdx Phenotype through Modulation of Inflammation. Hyzewicz J, Tanihata J, Kuraoka M, Nitahara-Kasahara Y, Beylier T, Ruegg UT, Vater A, Takeda S. The American journal of pathology. 2017 May;187:1147-1161. (Human) [Full Text Article] [PubMed:28315675] Related Antibodies: LS-C144479.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
MYBPC1 (5)
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GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (3)
Mouse (1)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
MYBPC1 Protein - Purified recombinant protein MYBPC1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
126.3 kDa
20 µg/$1,107
MYBPC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
126.3 kDa
100 µg/$710
MYBPC1 Protein - Recombinant Myosin Binding Protein C, Slow Type By SDS-PAGE
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E. coli
His-T7
35.2 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
MYBPC1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MYBPC1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
126.3 kDa
20 µg/$215
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).