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MYB / c-Myb
v-myb avian myeloblastosis viral oncogene homolog
MYB / c-Myb is a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
| Gene Name: | v-myb avian myeloblastosis viral oncogene homolog |
| Synonyms: | MYB, C-myb_CDS, C-myb8B_CDS, C-myb protein (140 AA), C-myb10A_CDS, C-myb13A_CDS, Efg, Transcriptional activator Myb, C-myb, C-myb14A_CDS, Cmyb, Proto-oncogene c-Myb |
| Target Sequences: | NM_005375 NP_005366.2 P10242 |
Publications (4)
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