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MXI1 / MAD2

MAX interactor 1, dimerization protein

Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Gene Name: MAX interactor 1, dimerization protein
Synonyms: MXI1, BHLHc11, MAX dimerization protein 2, MAX interactor 1, MAD2, MXI, MAX interacting protein 1, MXD2, Max-interacting protein 1
Target Sequences: NM_005962 NP_005953.4 P50539

☰ Filters
Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
MXI1 / MAD2 (8)
No (8)
GST (2)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
Myc-DDK (Flag) (4)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (2)
MXI1 / MAD2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
20.4 kDa
100 µg/$494
MXI1 / MAD2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32.6 kDa
100 µg/$494
MXI1 / MAD2 Protein
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E. coli
GST, N-terminus + His, C-terminus
48.4 kDa
50 µg/$419
MXI1 / MAD2 Protein - 12.5% SDS-PAGE of human MXI1 stained with Coomassie Blue
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Wheat Germ Extract
GST
45.76 kDa
10 µg/$479; 25 µg/$670
MXI1 / MAD2 Protein - 12.5% SDS-PAGE of human MXI1 stained with Coomassie Blue
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Wheat Germ Extract
GST
52.5 kDa
10 µg/$479; 25 µg/$670
MXI1 / MAD2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MXI1 / MAD2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
20.4 kDa
20 µg/$150
MXI1 / MAD2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
32.6 kDa
20 µg/$150
Viewing 1-8 of 8 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).