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Transcriptional repressor. Binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation.
Gene Name: | MAX dimerization protein 3 |
Synonyms: | MXD3, BHLHC13, MAD3, MAX dimerization protein 3, MYX, Max dimerizer 3, Max-associated protein 3 |
Target Sequences: | NM_031300 NP_112590.1 Q9BW11 |
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