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MUTYH / MYH

mutY homolog

MUTYH is a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: mutY homolog
Synonyms: MUTYH, HMYH, MYH, MutY (E. coli) homolog, CYP2C, MutY homolog, MutY homolog (E. coli)
Target Sequences: NM_012222 NP_036354.1 Q9UIF7

Publications (1)

1
Variation in MUTYH expression in Arabian horses with Cerebellar Abiotrophy. Scott EY, Woolard KD, Finno CJ, Penedo MCT, Murray JD. Brain research. 2018 January;1678:330-336. [Full Text Article] [PubMed:29103988] [PMC:PMC5905334] Related Antibodies: LS-C354036.

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Antibodies (30)
Primary (30)
MUTYH / MYH (30)
Human (30)
Mouse (12)
Rat (10)
Bovine (1)
Cat (1)
Chicken (1)
Dog (1)
Donkey (1)
Goat (1)
Guinea pig (1)
Hamster (1)
Horse (1)
Monkey (2)
Pig (1)
Rabbit (1)
Sheep (1)
IHC (9)
IHC-P (4)
WB (30)
Flo (1)
ELISA (11)
ICC (2)
IF (9)
IP (2)
Peptide-ELISA (4)
RNAi (1)
rabbit (27)
mouse (1)
goat (2)
Product Group
IHCPlus (1)
IgG (15)
IgG1,k (1)
monoclonal mc (1)
polyclonal pc (29)
4D10 (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (1)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (23)
aa351-544 (8)
C-Terminus (2)
120-200 aa, Internal (1)
Internal (1)
N-Terminus (1)
Tyr176 (1)
aa1-265 (1)
aa127-176 (1)
aa151-200 (1)
aa341-367 (1)
aa531-546 (1)
aa533-546 (1)
No (29)
Yes (1)
MUTYH / MYH Antibody - Immunohistochemical analysis of MUTYH staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MUTYH / MYH Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
MUTYH / MYH Antibody - Anti-MUTYH antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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MUTYH / MYH Rabbit anti-Human Polyclonal (aa531-546) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µg/$460
MUTYH / MYH Antibody - Confocal immunofluorescence of MUTYH Antibody with HeLa cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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MUTYH / MYH Rabbit anti-Human Polyclonal (aa341-367) Antibody
Mouse, Human
Flo, IF, WB
Unconjugated
400 µl/$393
MUTYH / MYH Antibody - Western blot of MYH antibody
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MUTYH / MYH Rabbit anti-Human Polyclonal (120-200 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MUTYH / MYH Antibody - MUTYH monoclonal antibody (M01), clone 4D10 Western Blot analysis of MUTYH expression in HeLa NE.
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MUTYH / MYH Mouse anti-Human Monoclonal (4D10) Antibody
Human
ELISA, IP, RNAi, WB
Unconjugated
100 µg/$423
MUTYH / MYH Antibody - Immunohistochemistry of paraffin-embedded human colon cancer using antibody at 1:100 dilution.
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MUTYH / MYH Rabbit anti-Human Polyclonal (aa1-265) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
MUTYH / MYH Antibody - IHC of MYH (Y176) pAb in paraffin-embedded human colon carcinoma tissue.
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MUTYH / MYH Rabbit anti-Human Polyclonal (Tyr176) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
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MUTYH / MYH Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
MUTYH / MYH Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using MUTYH Polyclonal Antibody at dilution of 1:25.
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MUTYH / MYH Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MUTYH / MYH Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using MUTYH Polyclonal Antibody at dilution of 1:60.
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MUTYH / MYH Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MUTYH / MYH Antibody - Immunofluorescence analysis of U20S cells.
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MUTYH / MYH Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
MUTYH / MYH Antibody - Western blot of HeLa cell lysate using MUTYH Antibody
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MUTYH / MYH Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
MUTYH / MYH Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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MUTYH / MYH Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MUTYH / MYH Antibody - Peptide - + Immunofluorescence analysis of A549 cells, using MUTYH antibody.
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MUTYH / MYH Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
MUTYH / MYH Antibody - Immunofluorescence analysis of A549 cells, using MUTYH Antibody. The picture on the right is blocked with the synthesized peptide.
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MUTYH / MYH Rabbit anti-Human Polyclonal (aa151-200) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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MUTYH / MYH Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
0.1 mg/$394
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MUTYH / MYH Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
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MUTYH / MYH Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
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MUTYH / MYH Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$832
MUTYH / MYH Antibody - Western blot analysis of the lysates from HUVECcells using MUTYH antibody.
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MUTYH / MYH Rabbit anti-Human Polyclonal (aa127-176) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MUTYH / MYH Antibody - Antibody (0.1 ug/ml) staining of Human Bone Marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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MUTYH / MYH Goat anti-Human Polyclonal (aa533-546) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
MUTYH / MYH Antibody - Western blot of MUTYH / MYH antibody.
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MUTYH / MYH Rabbit anti-Human Polyclonal (aa351-544) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
MUTYH / MYH Antibody - Western blot of MUTYH / MYH antibody.
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MUTYH / MYH Rabbit anti-Human Polyclonal (aa351-544) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
MUTYH / MYH Antibody - Western blot of MUTYH / MYH antibody.
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MUTYH / MYH Rabbit anti-Human Polyclonal (aa351-544) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
MUTYH / MYH Antibody - Western blot. Anti-Mutyh antibody at 1:1000 dilution. Recombinant protein at 50 ng and 293HEK transfected lysate at 100 ug per lane. Rabbit polyclonal to goat IgG (HRP) at 1:10000 dilution.
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MUTYH / MYH Goat anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Sheep, Bovine, Rabbit, Mouse, Goat, Dog, Guinea pig, Rat, Hamster, Pig, Cat, Horse, Donkey, Human, Monkey
WB
Unconjugated
600 µg/$409
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).