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MUC5B

mucin 5B, oligomeric mucus/gel-forming

MUC5B is a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.

Gene Name: mucin 5B, oligomeric mucus/gel-forming
Synonyms: MUC5B, MUC-5B, MUC9, Mucin-5B, Sublingual gland mucin, MG1, Cervical mucin, Cervical mucin MUC5B, MUC5
Target Sequences: NM_002458 NP_002449.2 Q9HC84

Publications (4)

1
Vagal sensory neurons drive mucous cell metaplasia. Sébastien Talbot, Benjamin Doyle, Junwei Huang, Jo-Chiao Wang, Maryam Ahmadi, David P Roberson, Ajay Yekkirala, Simmie L Foster, Liam E Browne, Bruce P Bean, Bruce D Levy, Clifford J Woolf. The Journal of allergy and clinical immunology. 2020 June;145:1693-1696.e4. [Full Text Article] [PubMed:31954778]
2
Combined Expression of Plasma Thrombospondin-2 and CA19-9 for Diagnosis of Pancreatic Cancer and Distal Cholangiocarcinoma: A Proteome Approach. Tessa Y S Le Large , Laura L Meijer , Rosita Paleckyte, Lenka N C Boyd, Bart Kok, Thomas Wurdinger, Tim Schelfhorst, Sander R Piersma, Thang V Pham, Nicole C T van Grieken, Barbara M Zonderhuis, Freek Daams, Hanneke W M van Laarhoven, Maarten F Bijlsma, Connie R Jimenez, Elisa Giovannetti , Geert Kazemier. The oncologist. 2020 Apr;25:e634-e643. [Full Text Article] [PubMed:31943574] [PMC:PMC7160420]
3
Quantification of very late xerostomia in head and neck cancer patients after irradiation. Grace C Blitzer, Nicole M Rogus-Pulia, Cristina Paz, Kwangok P Nickel, Vanessa L Cannaday, Cynthia A Kelm-Nelson, Sailendharan Sudakaran, Richard J Chappell, Tiffany Glazer, Randall J Kimple. Laryngoscope investigative otolaryngology. 2022 August;7:1018-1024. [Full Text Article] [PubMed:36000048] [PMC:PMC9392383]
4
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways. Yan Shin J Liao, Shin Ping Kuan, Maria V Guevara, Emily N Collins, Kalina R Atanasova, Joshua S Dadural, Kevin Vogt, Veronica Schurmann, Laura Bravo, Eda Eken, Mariana Sponchiado, Leah R Reznikov. American journal of physiology. Lung cellular and molecular physiology. 2020 May;318:L873-L887. [Full Text Article] [PubMed:32160007] [PMC:PMC7272746]
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ELISA Kits (21)
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MUC5B (21)
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Mouse (5)
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DevKit DuoPlus (2)
12 x 8-Well Microstrips (2)
96-Well Microplate (2)
96-Well Strip Plate (14)
Antibody Pair and Standard (3)
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Yes (3)
Cell Culture Supernatants (6)
Cell Lysates (6)
Plasma (9)
Serum (9)
Tissue Homogenates (8)
MUC5B ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
MUC5B ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$771
MUC5B ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
125 - 8000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$863
MUC5B ELISA Kit
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Sandwich
96-Well Microplate
Human
0.63 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
MUC5B ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$764
MUC5B ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$705
MUC5B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
MUC5B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$958
MUC5B ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
MUC5B ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Human
54.9 - 40000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$968
MUC5B ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$818
Select
Development Kit
Antibody Pair and Standard
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
500 Wells/$1,296; 1000 Wells/$1,708
MUC5B ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Mouse
1.25 - 80 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,109; 1000 Wells/$1,625
MUC5B ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
MUC5B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
MUC5B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
MUC5B ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$760
MUC5B ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
MUC5B ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
MUC5B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
MUC5B ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,254; 1000 Wells/$1,867
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).