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MUC5B

mucin 5B, oligomeric mucus/gel-forming

MUC5B is a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases.

Gene Name: mucin 5B, oligomeric mucus/gel-forming
Synonyms: MUC5B, MUC-5B, MUC9, Mucin-5B, Sublingual gland mucin, MG1, Cervical mucin, Cervical mucin MUC5B, MUC5
Target Sequences: NM_002458 NP_002449.2 Q9HC84

Publications (4)

1
Vagal sensory neurons drive mucous cell metaplasia. Sébastien Talbot, Benjamin Doyle, Junwei Huang, Jo-Chiao Wang, Maryam Ahmadi, David P Roberson, Ajay Yekkirala, Simmie L Foster, Liam E Browne, Bruce P Bean, Bruce D Levy, Clifford J Woolf. The Journal of allergy and clinical immunology. 2020 June;145:1693-1696.e4. [Full Text Article] [PubMed:31954778]
2
Combined Expression of Plasma Thrombospondin-2 and CA19-9 for Diagnosis of Pancreatic Cancer and Distal Cholangiocarcinoma: A Proteome Approach. Tessa Y S Le Large , Laura L Meijer , Rosita Paleckyte, Lenka N C Boyd, Bart Kok, Thomas Wurdinger, Tim Schelfhorst, Sander R Piersma, Thang V Pham, Nicole C T van Grieken, Barbara M Zonderhuis, Freek Daams, Hanneke W M van Laarhoven, Maarten F Bijlsma, Connie R Jimenez, Elisa Giovannetti , Geert Kazemier. The oncologist. 2020 Apr;25:e634-e643. [Full Text Article] [PubMed:31943574] [PMC:PMC7160420]
3
Quantification of very late xerostomia in head and neck cancer patients after irradiation. Grace C Blitzer, Nicole M Rogus-Pulia, Cristina Paz, Kwangok P Nickel, Vanessa L Cannaday, Cynthia A Kelm-Nelson, Sailendharan Sudakaran, Richard J Chappell, Tiffany Glazer, Randall J Kimple. Laryngoscope investigative otolaryngology. 2022 August;7:1018-1024. [Full Text Article] [PubMed:36000048] [PMC:PMC9392383]
4
Acid exposure disrupts mucus secretion and impairs mucociliary transport in neonatal piglet airways. Yan Shin J Liao, Shin Ping Kuan, Maria V Guevara, Emily N Collins, Kalina R Atanasova, Joshua S Dadural, Kevin Vogt, Veronica Schurmann, Laura Bravo, Eda Eken, Mariana Sponchiado, Leah R Reznikov. American journal of physiology. Lung cellular and molecular physiology. 2020 May;318:L873-L887. [Full Text Article] [PubMed:32160007] [PMC:PMC7272746]
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Antibodies (74)
Primary (74)
MUC5B (74)
Human (29)
Mouse (11)
Rat (27)
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Cow (8)
IHC (8)
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WB (69)
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ELISA (9)
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Peptide-ELISA (4)
rabbit (55)
mouse (16)
goat (3)
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IHCPlus (1)
IgG (2)
IgG1 (2)
IgG1,k (6)
monoclonal mc (16)
polyclonal pc (58)
5B19-2E (1)
6F8B2 (1)
7F5A1 (1)
APC (7)
APC Conjugated (8)
Biotin Conjugated (10)
Cy3 Conjugated (7)
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PE Conjugated (8)
Unconjugated (16)
aa898-1002 (10)
aa3513-3611 (8)
aa3667-3771 (8)
aa5366-5444 (8)
aa6489-6632 (8)
aa75-295 (8)
aa664-724 (2)
N-Terminus (1)
aa1232-1245 (1)
aa4698-4707 (1)
aa4756-4766 (1)
No (74)
MUC5B Antibody - Immunohistochemical analysis of paraffin-embedded rectum tissues using MUC5B mouse mAb with DAB staining.
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MUC5B Mouse anti-Human Monoclonal (7F5A1) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$459
MUC5B Antibody
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MUC5B Rabbit anti-Mouse Polyclonal (aa75-295) Antibody
Mouse
WB
Unconjugated
100 µl/$291; 200 µl/$326; 500 µl/$441; 1 ml/$499; 2 ml/$622; 5 ml/$1,067
MUC5B Antibody
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MUC5B Rabbit anti-Mouse Polyclonal (aa75-295) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$324; 200 µl/$372; 500 µl/$533; 1 ml/$622; 2 ml/$854; 5 ml/$1,412
MUC5B Antibody - Western blot of recombinant MUC5B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MUC5B Rabbit anti-Human Polyclonal (aa5366-5444) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
MUC5B Antibody - Western blot of recombinant MUC5B.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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MUC5B Rabbit anti-Human Polyclonal (aa5366-5444) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217
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MUC5B Mouse anti-Human Monoclonal (N-Terminus) (5B19-2E) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$842
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MUC5B Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated
100 µl/$1,063
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MUC5B Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
100 µl/$1,063
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MUC5B Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
100 µl/$1,063
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MUC5B Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
100 µl/$1,063
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MUC5B Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
100 µl/$1,063
MUC5B Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
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MUC5B Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
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MUC5B Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µl/$305; 200 µl/$345; 500 µl/$479; 1 ml/$547; 2 ml/$725; 5 ml/$1,192
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MUC5B Mouse anti-Human Monoclonal (HRP) Antibody
Human
ICC, IP, WB
HRP Conjugated
100 µl/$333; 200 µl/$385; 500 µl/$560; 1 ml/$672; 2 ml/$909; 5 ml/$1,529
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MUC5B Mouse anti-Human Monoclonal (FITC) Antibody
Human
ICC, IP, WB
FITC Conjugated
100 µl/$342; 200 µl/$399; 500 µl/$587; 1 ml/$725; 2 ml/$962; 5 ml/$1,647
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MUC5B Mouse anti-Human Monoclonal (PE) Antibody
Human
ICC, IP, WB
PE Conjugated
100 µl/$399; 200 µl/$479; 500 µl/$822; 1 ml/$978; 2 ml/$1,255; 5 ml/$2,353
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MUC5B Mouse anti-Human Monoclonal (APC, Cy7) Antibody
Human
ICC, IP, WB
APC, Cy7 Conjugated
100 µl/$493; 200 µl/$622; 500 µl/$1,118; 1 ml/$1,345; 2 ml/$1,883; 5 ml/$3,529
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MUC5B Mouse anti-Human Monoclonal (Cy3) Antibody
Human
ICC, IP, WB
Cy3 Conjugated
100 µl/$399; 200 µl/$479; 500 µl/$822; 1 ml/$978; 2 ml/$1,255; 5 ml/$2,353
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MUC5B Mouse anti-Human Monoclonal (APC) Antibody
Human
ICC, IP, WB
APC Conjugated
100 µl/$399; 200 µl/$479; 500 µl/$822; 1 ml/$978; 2 ml/$1,255; 5 ml/$2,353
MUC5B Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer using MUC5B Polyclonal Antibody at dilution of 1:70.
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MUC5B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MUC5B Antibody - Goat Anti-Muc5b (mouse) Antibody Immunofluorescence analysis of paraformaldehyde fixed NIH3T3 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing vesicle staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml).
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MUC5B Goat anti-Mouse Polyclonal (aa4756-4766) Antibody
Mouse
Peptide-ELISA
Unconjugated
100 µg/$503
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MUC5B Rabbit anti-Human Polyclonal Antibody
Human
IHC-P
Unconjugated
100 µg/$357
MUC5B Antibody - Western Blot; Sample: Recombinant MUC5B, Rat.
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MUC5B Rabbit anti-Rat Polyclonal (aa898-1002) Antibody
Rat
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
MUC5B Antibody - Western Blot; Sample: Recombinant MUC5B, Rat.
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MUC5B Rabbit anti-Rat Polyclonal (aa898-1002) (APC) Antibody
Rat
WB
APC Conjugated
100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395
MUC5B Antibody - Western blot analysis using MUC5B mAb against HEK293 (1) and MUC5B (AA: 26-166)-hIgGFc transfected HEK293 (2) cell lysate.
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MUC5B Mouse anti-Human Monoclonal (6F8B2) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$459
Viewing 1-25 of 74 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).