MTHFD1

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase

MTHFD1 encodes a protein that possesses three distinct enzymatic activities, 5,10-methylenetetrahydrofolate dehydrogenase, 5,10-methenyltetrahydrofolate cyclohydrolase and 10-formyltetrahydrofolate synthetase. Each of these activities catalyzes one of three sequential reactions in the interconversion of 1-carbon derivatives of tetrahydrofolate, which are substrates for methionine, thymidylate, and de novo purine syntheses. The trifunctional enzymatic activities are conferred by two major domains, an aminoterminal portion containing the dehydrogenase and cyclohydrolase activities and a larger synthetase domain.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

MTHFD1 (5)

Publications

No (5)

Tag

6His-SUMO, N-terminus (1)

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Orangutan (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human MTHFD1 Protein (Recombinant GST) (Full Length) - LS-G29394

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

128.59 kDa

Price:

10 µg/$479; 25 µg/$670

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Human MTHFD1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65105

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

101.4 kDa

Price:

20 µg/$1,107

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Orangutan MTHFD1 Protein (Recombinant 6His-SUMO, N-terminus) - LS-G136464

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Molecular Weight:

49.0kDa

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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MTHFD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115622

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

101.4 kDa

Price:

100 µg/$494

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Human MTHFD1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74868

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

101.4 kDa

Price:

20 µg/$150

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